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The safety and effectiveness for use in the lips has not been established. There have been published reports of nodules associated with the use of these products injected into the lips.

Severity of Wrinkles/Lines: Deeper, more established wrinkles that are present even when the face is at rest (static lines) might require more units than finer lines that only appear with movement (dynamic lines).

Pelo definitive serious adverse event reports of distant spread of toxin effect associated with BOTOX for blepharospasm at the recommended dose (30 Units and below), severe primary axillary hyperhidrosis at the recommended dose (cem Units), strabismus, or for chronic migraine at the labeled doses have been reported.

Please see the Patient Information Guide available at for list of these events. Tell your health care provider about any side effects that bother you or do not go away.

If injection sites are marked in ink, do not inject BOTOX directly through the ink mark to avoid a permanent tattoo effect.

Botox for medical conditions should only be injected by a trained healthcare provider who can ensure:

Patients who are using medications that can prolong bleeding, such as aspirin or warfarin, may experience increased bruising or bleeding at the injection sitio.

The potency Units of BOTOX (onabotulinumtoxinA) for injection are specific to the preparation and assay method utilized. They are not interchangeable with other preparations of botulinum toxin products and, therefore, units of biological activity of BOTOX cannot be compared to nor converted into units of any other botulinum toxin products assessed with any other specific assay method.

That’s probably no surprise—but do you know exactly how? Two important components are collagen and elastin, which help keep botox facial lines and wrinkles at bay.

Botox Cosmetic and Botox come as separate products but are both prescription medicines that contain the active ingredient onabotulinumtoxinA. Continue reading

Localization of the involved muscles with techniques such as needle electromyographic guidance, nerve stimulation, or ultrasound is recommended. When treating both lower limbs or the upper and lower limbs in combination, the Perfeito dose should not exceed the lower of 10 Units/kg body weight or 340 Units, in a 3-month interval.

RADIESSE® is also used for correcting volume loss in the back of the hands. RADIESSE® (+) is also used for improving moderate to severe loss of jawline contour in adults over 21 years old.

The initial dose for a patient without prior use of BOTOX should be at a lower dose, with subsequent dosing adjusted based on individual response. Limiting the Perfeito dose injected into the sternocleidomastoid muscle to cem Units or less may decrease the occurrence of dysphagia.

The safety and effectiveness of RADIESSE® or RADIESSE® (+) in the following situations has not been established:

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